Traditionally, it has become generally believed that when women ages, their eggs start to decrease, and egg quality also drops, which makes it difficult for women to become pregnant or carry pregnancy to semester, especially after 35. A new study, however, has probably reversed the story of male and female fertility patterns. Research conducted in 2025 shows that women maintain a stable egg quality throughout their lives, despite common misconceptions. The scientific evidence shows that sperm quality in men is significantly deteriorating with age and thus disproves the traditional belief that fertility issues mainly affect women.The traditional viewWomen’s fertility has remained close to their age for several decades. The biological clock concept has remained as a widespread faith, which says that women experience rapid egg quantity and quality deterioration after reaching their late 30s or early 40s. The cause of women’s declining fertility during the late 30s and 40s became clear, as their egg quality and quantity decrease, and their risk of miscarriage and sub -syndrome increases.
On the other hand, the general view of male fertility showed that the sperm quality remained stable until men reached an advanced age. The medical world directed most of its fertility warnings and reproductive health interventions towards women through egg freezing programs.Turn the story2025 Science Advances Journal Published research from Penn State University, which challenged traditional beliefs of human biological aging. The research team analyzed mitochondrial DNA mutations in eggs from women between 22 and 42 years old and compared these results with mutations found in different body cell types.The energy-producing structures called mitochondria contain their own small DNA sequences within cells. Researchers understand that mitochondrial DNA accumulates age -related mutations, leading to cell performance. The researchers predicted that older women’s eggs would contain elevated mitochondrial DNA mutations, which would lead to reduced fertility with age.The research team discovered that human egg cells maintain stable mitochondrial DNA mutation levels during a woman’s life. The research indicates that human eggs maintain its mitochondrial DNA quality at a consistent level through ages 22 to 42. The mutation frequency in eggs remained constantly in all age groups, while blood and saliva cells showed 17 to 24 times more mutations. The eggs have natural defenses that protect them from acquiring these mutations.
The research results indicate that women’s egg cells maintain their mitochondrial quality at a consistent level during their reproductive years up to 42 years. However, the study results do not indicate that women will not experience any changes in their fertility. The quality of eggs depends on nuclear power -DNA mutations, which affect fertility and increase the risk of miscarriage. The research shows that mitochondrial mutations do not act as the primary factor behind decreasing female fertility with age, but genetic factors continue to affect fertility and miscarriage risks.The study shows that women experience biological age -related fertility problems, but their eggsmitochondria maintain better stability than researchers who originally believed.Men also have a biological watchThe scientific evidence Shows that sperm quality in men is significantly impaired by increasing age. The process of sperm generation in the body leads to DNA mutation acumulation in the meantime. The genetic errors found in older sperm cells adversely affect fertility and lead to negative pregnancy results and potential health problems in children.Research As conducted in 2025, paternal age created higher chances for miscarriage and neurut development disorders, including autism in children. The study confirms that men experience a significant biological time limit that affects their reproductive abilities.What that meansThe research results provide significant knowledge for people who want to start a family. The research notes that women’s egg quality remains somewhat stable, but still deteriorates men’s sperm quality with age and thus requires equal attention to both reproductive health aspects.The knowledge of shared fertility issues should reach all couples who plan to start a family. Men who postpone paternity will experience higher risks from sperm, which parallel to fertility problems that women encounter because of their age.Tips for maintaining fertilityWomen must keep their gynecological meetings regularly, while receiving fertility tests when they reach their advanced age.Men must have fertility tests before deciding to become fathers when they reach older age.A combination of exercise and proper nutrition, without smoking and controlled alcohol consumption, leads to better reproductive health for both men and women.The degree of success for IVF treatments improves when couples understand the biological characteristics of both partners.Disclaimer clause: This article is only informative and not a compensation for medical advice
